News

Healthtech Startup Avammune Bags $12 Mn From Capital 2B, Others

Publications

AVA-NP-695 Selectively Inhibits ENPP1 to Activate STING Pathway and Abrogate Tumor Metastasis in 4T1 Breast Cancer Syngeneic Mouse Model.
Avijit Goswami, Barnali Deb, Sandeep Goyal, Abhishek Gosavi, Mukund Mali, Ashwita M. Martis, Princy Khurana, Mukesh Gangar, Digambar Raykar, Ankita Mohanty and Aditya Kulkarni

Molecules. October 2022, 27, 6721

Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy.
Mukesh Gangar, Sandeep Goyal, Digambar Raykar, Princy Khurana, Ashwita M. Martis, Avijit Goswami, Ishani Ghoshal, Ketul V. Patel, Yadav Nagare, Santosh Raikar, Apurba Mukherjee, Rajath Cyriac, Jean-François Paquin, Aditya Kulkarni

Bioorganic Chemistry. December 2021, 0045-2068/© 2021 Elsevier Inc.

Conference Abstracts

Abstract 3095: Development of a novel ADAR1 inhibitor as a potent immunomodulator for the treatment of solid tumors
Aditya Kulkarni, Avijit Goswami, Sandeep Goyal, Kawaljit Singh, Princy Khurana, Ishani Ghoshal

Journal: Cancer Research Cancer Res (2023) 83 (7_Supplement): 3095. https://doi.org/10.1158/1538-7445.AM2023-3095

1335 AVA-NP-695 potently and selectively inhibits ENPP1 to activate STING pathway and abrogate tumor metastasis in 4T1 breast cancer syngeneic mouse model
AdityaKulkarni, Avijit Goswami, Sandeep Goyal, Princy Khurana, Arun Papaiah

Journal for ImmunoTherapy of Cancer Nov 2022, 10 (Suppl 2) A1386; DOI:10.1136/jitc-2022-SITC2022.1335

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